<link href="//maxcdn.bootstrapcdn.com/bootstrap/4.1.1/css/bootstrap.min.css" rel="stylesheet" id="bootstrap-css">
<script src="//maxcdn.bootstrapcdn.com/bootstrap/4.1.1/js/bootstrap.min.js"></script>
<script src="//cdnjs.cloudflare.com/ajax/libs/jquery/3.2.1/jquery.min.js"></script>
<!------ Include the above in your HEAD tag ---------->
Title and abstract screening
<!-- Multiple Radios -->
<div class="form-group">
<label class="col-md-4 control-label" for="radios">1. Is the study an in vivo animal research with SNI, PSL or CCI models of neuropathic pain?</label>
<div class="col-md-4">
<div class="radio">
<label for="radios-0">
<input type="radio" name="radios" id="radios-0" value="1" checked="checked">
Yes
</label>
</div>
<div class="radio">
<label for="radios-1">
<input type="radio" name="radios" id="radios-1" value="2">
No
</label>
</div>
</div>
</div>
<!-- Textarea -->
<div class="form-group">
<label class="col-md-4 control-label" for="textarea">Explanation box</label>
<div class="col-md-4">
<textarea class="form-control" id="textarea" name="textarea">- SNI= Spared Nerve Injury- Decosterd_Woolf_2000;
- CCI= Chronic Constriction Injury (and all varieties);
- PSL= Partial Sciatic nerve Ligation)
</textarea>
</div>
</div>
<!-- Multiple Radios -->
<div class="form-group">
<label class="col-md-4 control-label" for="radios">2. Does the study use mice (mus musculus) or rats (rattus norvegicus forma domestica) or both?</label>
<div class="col-md-4">
<div class="radio">
<label for="radios-0">
<input type="radio" name="radios" id="radios-0" value="1" checked="checked">
Yes
</label>
</div>
<div class="radio">
<label for="radios-1">
<input type="radio" name="radios" id="radios-1" value="2">
No
</label>
</div>
</div>
</div>
<!-- Multiple Radios -->
<div class="form-group">
<label class="col-md-4 control-label" for="radios">3. Is the study an original primary research article? </label>
<div class="col-md-4">
<div class="radio">
<label for="radios-0">
<input type="radio" name="radios" id="radios-0" value="1" checked="checked">
Yes
</label>
</div>
<div class="radio">
<label for="radios-1">
<input type="radio" name="radios" id="radios-1" value="2">
No
</label>
</div>
</div>
</div>
Full text screening
<!-- Multiple Radios -->
<div class="form-group">
<label class="col-md-4 control-label" for="radios">1. Is the study an in vivo animal research with SNI, PSL or CCI models of neuropathic pain?</label>
<div class="col-md-4">
<div class="radio">
<label for="radios-0">
<input type="radio" name="radios" id="radios-0" value="1" checked="checked">
Yes
</label>
</div>
<div class="radio">
<label for="radios-1">
<input type="radio" name="radios" id="radios-1" value="2">
No
</label>
</div>
</div>
</div>
<!-- Textarea -->
<div class="form-group">
<label class="col-md-4 control-label" for="textarea">Explanation box</label>
<div class="col-md-4">
<textarea class="form-control" id="textarea" name="textarea">- SNI= Spared Nerve Injury- Decosterd_Woolf_2000;
- CCI= Chronic Constriction Injury (and all varieties);
- PSL= Partial Sciatic nerve Ligation)
</textarea>
</div>
</div>
<!-- Multiple Radios -->
<div class="form-group">
<label class="col-md-4 control-label" for="radios">2. There is at least one pain-related behavioural assessment reported in the study?</label>
<div class="col-md-4">
<div class="radio">
<label for="radios-0">
<input type="radio" name="radios" id="radios-0" value="1" checked="checked">
Yes
</label>
</div>
<div class="radio">
<label for="radios-1">
<input type="radio" name="radios" id="radios-1" value="2">
No
</label>
</div>
</div>
</div>
<!-- Multiple Radios -->
<div class="form-group">
<label class="col-md-4 control-label" for="radios">3. Are there at least TWO times of assessment?</label>
<div class="col-md-4">
<div class="radio">
<label for="radios-0">
<input type="radio" name="radios" id="radios-0" value="1" checked="checked">
Yes
</label>
</div>
<div class="radio">
<label for="radios-1">
<input type="radio" name="radios" id="radios-1" value="2">
No
</label>
</div>
</div>
</div>
<!-- Multiple Radios -->
<div class="form-group">
<label class="col-md-4 control-label" for="radios">4. Is the study an original primary research article? (No review, no book chapters, no congress abstracts) </label>
<div class="col-md-4">
<div class="radio">
<label for="radios-0">
<input type="radio" name="radios" id="radios-0" value="1" checked="checked">
Yes
</label>
</div>
<div class="radio">
<label for="radios-1">
<input type="radio" name="radios" id="radios-1" value="2">
No
</label>
</div>
</div>
</div>
Neuropathic SLR disease model induction
<!-- Select Basic -->
<div class="form-group"><label class="col-md-4 control-label" for="selectbasic">0. Procedure label: What is the type of neuropathic pain model? </label>
<div class="col-md-4"><select id="selectbasic" name="selectbasic" class="form-control">
<option value="1">SNI</option>
<option value="2">PSL or PSNL</option>
<option value="3">CCI (all variants)</option>
</select><em><span class="help-block">List the disease or injury that is being modelled; Provide a label to uniquely identify a disease model induction procedure within the study </span></em></div>
</div>
<!-- Appended checkbox -->
<div class="form-group"><label class="col-md-4 control-label" for="appendedcheckbox">1. Control Procedure?</label>
<div class="col-md-4">
<div class="input-group"><input id="appendedcheckbox" name="appendedcheckbox" class="form-control" type="text" placeholder="Yes" /> <span class="input-group-addon"> <input type="checkbox" /> </span></div>
<p class="help-block"><em>Is this a control procedure for the disease model induction?</em></p>
</div>
</div>
<!-- Multiple Radios (inline) -->
<div class="form-group"><label class="col-md-4 control-label" for="radios">1a. Was a sham surgery preformed?</label>
<div class="col-md-4"><label class="radio-inline" for="radios-0"> <input type="radio" name="radios" id="radios-0" value="1" checked="checked" /> Yes </label> <label class="radio-inline" for="radios-1"> <input type="radio" name="radios" id="radios-1" value="2" /> No </label> <label class="radio-inline" for="radios-2"> <input type="radio" name="radios" id="radios-2" value="3" /> Not reported </label> <em><span class="help-block">Did the animals allocated to the control group undergo a surgical procedure </span></em></div>
</div>
<!-- Multiple Radios (inline) -->
<div class="form-group"><label class="col-md-4 control-label" for="radios">1b. Was a naive animal used as control?</label>
<div class="col-md-4"><label class="radio-inline" for="radios-0"> <input type="radio" name="radios" id="radios-0" value="1" checked="checked" /> Yes </label> <label class="radio-inline" for="radios-1"> <input type="radio" name="radios" id="radios-1" value="2" /> No </label> <label class="radio-inline" for="radios-2"> <input type="radio" name="radios" id="radios-2" value="3" /> Not reported </label> <em><span class="help-block">Answer yes if a healthy animal that did not undergo sham surgery or treatment was used as the control </span></em></div>
</div>
<!-- Multiple Radios (inline) -->
<div class="form-group"><label class="col-md-4 control-label" for="radios">1c. Was the contralateral side used as control?</label>
<div class="col-md-4"><label class="radio-inline" for="radios-0"> <input type="radio" name="radios" id="radios-0" value="1" checked="checked" /> Yes </label> <label class="radio-inline" for="radios-1"> <input type="radio" name="radios" id="radios-1" value="2" /> No </label> <label class="radio-inline" for="radios-2"> <input type="radio" name="radios" id="radios-2" value="3" /> Not reported </label> <em><span class="help-block">Answer yes if the contralateral side used as the control </span></em></div>
</div>
<!-- Select Basic -->
<div class="form-group"><label class="col-md-4 control-label" for="selectbasic">2. Was anaesthetic used? </label>
<div class="col-md-4"><select id="selectbasic" name="selectbasic" class="form-control">
<option value="1">Isoflurane</option>
<option value="2">KetamineL</option>
<option value="3">Ketamine/Xylazine</option>
<option value="4">Others</option>
<option value="5">Not reported</option>
</select><em><span class="help-block">List the disease or injury that is being modelled </span></em></div>
</div>
<!-- Text input-->
<div class="form-group"><label class="col-md-4 control-label" for="textinput">2a. If others, please specify the substance from the study text</label>
<div class="col-md-4"><input id="textinput" name="textinput" type="text" placeholder=" " class="form-control input-md" /> <em><span class="help-block">Please specify the substance from the study text </span></em></div>
</div>
<!-- Multiple Radios (inline) -->
<div class="form-group"><label class="col-md-4 control-label" for="radios">3. Was pre-operative analgesia administered?</label>
<div class="col-md-4"><label class="radio-inline" for="radios-0"> <input type="radio" name="radios" id="radios-0" value="1" checked="checked" /> Yes </label> <label class="radio-inline" for="radios-1"> <input type="radio" name="radios" id="radios-1" value="2" /> No </label> <label class="radio-inline" for="radios-2"> <input type="radio" name="radios" id="radios-2" value="3" /> Not reported </label> <em><span class="help-block">Were painkillers given pre surgery </span></em></div>
</div>
<!-- Text input-->
<div class="form-group"><label class="col-md-4 control-label" for="textinput">3a. If yes, What analgesic drug was used?</label>
<div class="col-md-4"><input id="textinput" name="textinput" type="text" placeholder=" " class="form-control input-md" /> <em><span class="help-block">Please specify the substance from the study text </span></em></div>
</div>
<!-- Textarea -->
<div class="form-group"><label class="col-md-4 control-label" for="textarea">3b. If yes, What dosage given for the painkiller?</label>
<div class="col-md-4"><textarea class="form-control" id="textarea" name="textarea">in mg/KG BW</textarea> <label class="radio-inline" for="radios-2"> <input type="radio" name="radios" id="radios-2" value="3" /> Not reported </label></div>
</div>
<!-- Text input-->
<div class="form-group"><label class="col-md-4 control-label" for="textinput">3c. If yes, How many times was the analgesic drug administered?</label>
<div class="col-md-4"><input id="textinput" name="textinput" type="text" placeholder=" " class="form-control input-md" /> <label class="radio-inline" for="radios-2"> <input type="radio" name="radios" id="radios-2" value="3" /> Not reported </label></div>
</div>
<!-- Multiple Radios (inline) -->
<div class="form-group"><label class="col-md-4 control-label" for="radios">3d. If yes, Which drug application route was used?</label>
<div class="col-md-4"><label class="radio-inline" for="radios-0"> <input type="radio" name="radios" id="radios-0" value="1" checked="checked" /> i.p. </label> <label class="radio-inline" for="radios-1"> <input type="radio" name="radios" id="radios-1" value="2" /> i.v. </label> <label class="radio-inline" for="radios-2"> <input type="radio" name="radios" id="radios-2" value="3" /> s.c. </label> <label class="radio-inline" for="radios-3"> <input type="radio" name="radios" id="radios-3" value="4" /> i.t. </label> <label class="radio-inline" for="radios-4"> <input type="radio" name="radios" id="radios-4" value="5" /> Others </label></div>
</div>
<!-- Text input-->
<div class="form-group"><label class="col-md-4 control-label" for="textinput">3e. If others, please specify the route from the study text</label>
<div class="col-md-4"><input id="textinput" name="textinput" type="text" placeholder=" " class="form-control input-md" /> <em><span class="help-block">Please specify the route from the study text </span></em></div>
</div>
<!-- Multiple Radios (inline) -->
<div class="form-group"><label class="col-md-4 control-label" for="radios">4. Was peri-operative analgesia administered?</label>
<div class="col-md-4"><label class="radio-inline" for="radios-0"> <input type="radio" name="radios" id="radios-0" value="1" checked="checked" /> Yes </label> <label class="radio-inline" for="radios-1"> <input type="radio" name="radios" id="radios-1" value="2" /> No </label> <label class="radio-inline" for="radios-2"> <input type="radio" name="radios" id="radios-2" value="3" /> Not reported </label> <em><span class="help-block">Were painkillers given during surgery </span></em></div>
</div>
<!-- Text input-->
<div class="form-group"><label class="col-md-4 control-label" for="textinput">4a. If yes, What analgesic drug was used?</label>
<div class="col-md-4"><input id="textinput" name="textinput" type="text" placeholder=" " class="form-control input-md" /> <em><span class="help-block">Please specify the substance from the study text </span></em></div>
</div>
<!-- Textarea -->
<div class="form-group"><label class="col-md-4 control-label" for="textarea">4b. If yes, What dosage given for the painkiller?</label>
<div class="col-md-4"><textarea class="form-control" id="textarea" name="textarea">in mg/KG BW</textarea> <label class="radio-inline" for="radios-2"> <input type="radio" name="radios" id="radios-2" value="3" /> Not reported </label></div>
</div>
<!-- Text input-->
<div class="form-group"><label class="col-md-4 control-label" for="textinput">4c. If yes, How many times was the analgesic drug administered?</label>
<div class="col-md-4"><input id="textinput" name="textinput" type="text" placeholder=" " class="form-control input-md" /> <label class="radio-inline" for="radios-2"> <input type="radio" name="radios" id="radios-2" value="3" /> Not reported </label></div>
</div>
<!-- Multiple Radios (inline) -->
<div class="form-group"><label class="col-md-4 control-label" for="radios">4d. If yes, Which drug application route was used?</label>
<div class="col-md-4"><label class="radio-inline" for="radios-0"> <input type="radio" name="radios" id="radios-0" value="1" checked="checked" /> i.p. </label> <label class="radio-inline" for="radios-1"> <input type="radio" name="radios" id="radios-1" value="2" /> i.v. </label> <label class="radio-inline" for="radios-2"> <input type="radio" name="radios" id="radios-2" value="3" /> s.c. </label> <label class="radio-inline" for="radios-3"> <input type="radio" name="radios" id="radios-3" value="4" /> i.t. </label> <label class="radio-inline" for="radios-4"> <input type="radio" name="radios" id="radios-4" value="5" /> Others </label></div>
</div>
<!-- Text input-->
<div class="form-group"><label class="col-md-4 control-label" for="textinput">4e. If others, please specify the route from the study text</label>
<div class="col-md-4"><input id="textinput" name="textinput" type="text" placeholder=" " class="form-control input-md" /> <em><span class="help-block">Please specify the route from the study text </span></em></div>
</div>
<!-- Multiple Radios (inline) -->
<div class="form-group"><label class="col-md-4 control-label" for="radios">5. Was post-operative analgesia administered?</label>
<div class="col-md-4"><label class="radio-inline" for="radios-0"> <input type="radio" name="radios" id="radios-0" value="1" checked="checked" /> Yes </label> <label class="radio-inline" for="radios-1"> <input type="radio" name="radios" id="radios-1" value="2" /> No </label> <label class="radio-inline" for="radios-2"> <input type="radio" name="radios" id="radios-2" value="3" /> Not reported </label> <em><span class="help-block">Were painkillers given post surgery </span></em></div>
</div>
<!-- Text input-->
<div class="form-group"><label class="col-md-4 control-label" for="textinput">5a. If yes, What analgesic drug was used?</label>
<div class="col-md-4"><input id="textinput" name="textinput" type="text" placeholder=" " class="form-control input-md" /> <em><span class="help-block">Please specify the substance from the study text </span></em></div>
</div>
<!-- Textarea -->
<div class="form-group"><label class="col-md-4 control-label" for="textarea">5b. If yes, What dosage given for the painkiller?</label>
<div class="col-md-4"><textarea class="form-control" id="textarea" name="textarea">in mg/KG BW</textarea> <label class="radio-inline" for="radios-2"> <input type="radio" name="radios" id="radios-2" value="3" /> Not reported </label></div>
</div>
<!-- Text input-->
<div class="form-group"><label class="col-md-4 control-label" for="textinput">5c. If yes, How many times was the analgesic drug administered?</label>
<div class="col-md-4"><input id="textinput" name="textinput" type="text" placeholder=" " class="form-control input-md" /> <label class="radio-inline" for="radios-2"> <input type="radio" name="radios" id="radios-2" value="3" /> Not reported </label></div>
</div>
<!-- Multiple Radios (inline) -->
<div class="form-group"><label class="col-md-4 control-label" for="radios">5d. If yes, Which drug application route was used?</label>
<div class="col-md-4"><label class="radio-inline" for="radios-0"> <input type="radio" name="radios" id="radios-0" value="1" checked="checked" /> i.p. </label> <label class="radio-inline" for="radios-1"> <input type="radio" name="radios" id="radios-1" value="2" /> i.v. </label> <label class="radio-inline" for="radios-2"> <input type="radio" name="radios" id="radios-2" value="3" /> s.c. </label> <label class="radio-inline" for="radios-3"> <input type="radio" name="radios" id="radios-3" value="4" /> i.t. </label> <label class="radio-inline" for="radios-4"> <input type="radio" name="radios" id="radios-4" value="5" /> Others </label></div>
</div>
<!-- Text input-->
<div class="form-group"><label class="col-md-4 control-label" for="textinput">5e. If others, please specify the route from the study text</label>
<div class="col-md-4"><input id="textinput" name="textinput" type="text" placeholder=" " class="form-control input-md" /> <em><span class="help-block">Please specify the route from the study text </span></em></div>
</div>
<!-- Multiple Radios (inline) -->
<div class="form-group"><label class="col-md-4 control-label" for="radios">6. Was perioperative antibiotica administered?</label>
<div class="col-md-4"><label class="radio-inline" for="radios-0"> <input type="radio" name="radios" id="radios-0" value="1" checked="checked" /> Yes </label> <label class="radio-inline" for="radios-1"> <input type="radio" name="radios" id="radios-1" value="2" /> No </label> <label class="radio-inline" for="radios-2"> <input type="radio" name="radios" id="radios-2" value="3" /> Not reported </label> <em><span class="help-block">Were antibiotica given during or immediately post surgery </span></em></div>
</div>
<!-- Text input-->
<div class="form-group"><label class="col-md-4 control-label" for="textinput">6a. If yes, What antibiotica was used?</label>
<div class="col-md-4"><input id="textinput" name="textinput" type="text" placeholder=" " class="form-control input-md" /> <em><span class="help-block">Please specify the anitbiotica from the study text </span></em></div>
</div>
<!-- Textarea -->
<div class="form-group"><label class="col-md-4 control-label" for="textarea">6b. If yes, What dosage given for the anitbiotica?</label>
<div class="col-md-4"><textarea class="form-control" id="textarea" name="textarea">in mg/KG BW</textarea> <label class="radio-inline" for="radios-2"> <input type="radio" name="radios" id="radios-2" value="3" /> Not reported </label></div>
</div>
<!-- Text input-->
<div class="form-group"><label class="col-md-4 control-label" for="textinput">6c. If yes, How many times was the antibiotica administered?</label>
<div class="col-md-4"><input id="textinput" name="textinput" type="text" placeholder=" " class="form-control input-md" /> <label class="radio-inline" for="radios-2"> <input type="radio" name="radios" id="radios-2" value="3" /> Not reported </label></div>
</div>
<!-- Multiple Radios (inline) -->
<div class="form-group"><label class="col-md-4 control-label" for="radios">6d. If yes, Which application route was used?</label>
<div class="col-md-4"><label class="radio-inline" for="radios-0"> <input type="radio" name="radios" id="radios-0" value="1" checked="checked" /> i.p. </label> <label class="radio-inline" for="radios-1"> <input type="radio" name="radios" id="radios-1" value="2" /> i.v. </label> <label class="radio-inline" for="radios-2"> <input type="radio" name="radios" id="radios-2" value="3" /> s.c. </label> <label class="radio-inline" for="radios-3"> <input type="radio" name="radios" id="radios-3" value="4" /> i.t. </label> <label class="radio-inline" for="radios-4"> <input type="radio" name="radios" id="radios-4" value="5" /> Others </label></div>
</div>
<!-- Text input-->
<div class="form-group"><label class="col-md-4 control-label" for="textinput">6e. If others, please specify the route from the study text</label>
<div class="col-md-4"><input id="textinput" name="textinput" type="text" placeholder=" " class="form-control input-md" /> <em><span class="help-block">Please specify the route from the study text </span></em></div>
</div>
<!-- Multiple Radios (inline) -->
<div class="form-group"><label class="col-md-4 control-label" for="radios">7. Did they specify how many ligations were made in the CCI model?</label>
<div class="col-md-4"><label class="radio-inline" for="radios-0"> <input type="radio" name="radios" id="radios-0" value="1" checked="checked" /> Yes </label> <label class="radio-inline" for="radios-1"> <input type="radio" name="radios" id="radios-1" value="2" /> No </label> <label class="radio-inline" for="radios-2"> <input type="radio" name="radios" id="radios-2" value="3" /> Not reported </label> <em><span class="help-block">The number does not matter. </span></em></div>
</div>
<!-- Text input-->
<div class="form-group"><label class="col-md-4 control-label" for="textinput">7a. If yes, How many ligatures were added to the CCI model?</label>
<div class="col-md-4"><input id="textinput" name="textinput" type="text" placeholder=" " class="form-control input-md" /> <label class="radio-inline" for="radios-2"> <input type="radio" name="radios" id="radios-2" value="3" /> Not reported </label></div>
</div>
<!-- Text input-->
<div class="form-group"><label class="col-md-4 control-label" for="textinput">7b. If yes, What material was used for the ligatures?</label>
<div class="col-md-4"><input id="textinput" name="textinput" type="text" placeholder=" " class="form-control input-md" /> <label class="radio-inline" for="radios-2"> <input type="radio" name="radios" id="radios-2" value="3" /> Not reported </label></div>
</div>
<!-- Multiple Radios (inline) -->
<div class="form-group"><label class="col-md-4 control-label" for="radios">8. Was the model duration reported?</label>
<div class="col-md-4"><label class="radio-inline" for="radios-0"> <input type="radio" name="radios" id="radios-0" value="1" checked="checked" /> Yes </label> <label class="radio-inline" for="radios-1"> <input type="radio" name="radios" id="radios-1" value="2" /> No </label> <label class="radio-inline" for="radios-2"> <input type="radio" name="radios" id="radios-2" value="3" /> Not reported </label></div>
</div>
<!-- Textarea -->
<div class="form-group"><label class="col-md-4 control-label" for="textarea">8a. If yes, What was the model duration</label>
<div class="col-md-4"><textarea class="form-control" id="textarea" name="textarea">Give the time in hours from model induction to end of experiment/euthanasia
</textarea></div>
</div>
<!-- Multiple Radios (inline) -->
<div class="form-group"><label class="col-md-4 control-label" for="radios">9. Was the the skin incision dimension described in cm?</label>
<div class="col-md-4"><label class="radio-inline" for="radios-0"> <input type="radio" name="radios" id="radios-0" value="1" checked="checked" /> Yes </label> <label class="radio-inline" for="radios-1"> <input type="radio" name="radios" id="radios-1" value="2" /> No </label> <label class="radio-inline" for="radios-2"> <input type="radio" name="radios" id="radios-2" value="3" /> Not reported </label></div>
</div>
<!-- Textarea -->
<div class="form-group"><label class="col-md-4 control-label" for="textarea">9a. If yes, How long was the skin incision in cm?</label>
<div class="col-md-4"><textarea class="form-control" id="textarea" name="textarea">in cm</textarea> <label class="radio-inline" for="radios-2"> <input type="radio" name="radios" id="radios-2" value="3" /> Not reported </label></div>
</div>
<!-- Multiple Radios (inline) -->
<div class="form-group"><label class="col-md-4 control-label" for="radios">10. Was the tissue closure procedure described?</label>
<div class="col-md-4"><label class="radio-inline" for="radios-0"> <input type="radio" name="radios" id="radios-0" value="1" checked="checked" /> Yes </label> <label class="radio-inline" for="radios-1"> <input type="radio" name="radios" id="radios-1" value="2" /> No </label> <label class="radio-inline" for="radios-2"> <input type="radio" name="radios" id="radios-2" value="3" /> Not reported </label></div>
</div>
<!-- Multiple Radios (inline) -->
<div class="form-group"><label class="col-md-4 control-label" for="radios">10a. If yes, Was the muscular layer closed?</label>
<div class="col-md-4"><label class="radio-inline" for="radios-0"> <input type="radio" name="radios" id="radios-0" value="1" checked="checked" /> Yes </label> <label class="radio-inline" for="radios-1"> <input type="radio" name="radios" id="radios-1" value="2" /> No </label> <label class="radio-inline" for="radios-2"> <input type="radio" name="radios" id="radios-2" value="3" /> Not reported </label></div>
</div>
<!-- Select Basic -->
<div class="form-group"><label class="col-md-4 control-label" for="selectbasic">10ai. If yes, what suture material was used to close the muscle layer? </label>
<div class="col-md-4"><select id="selectbasic" name="selectbasic" class="form-control">
<option value="1">Resorbable suture</option>
<option value="2">Non-absorbable suture</option>
<option value="3">Others</option>
</select><em><span class="help-block"> </span></em></div>
</div>
<!-- Multiple Radios (inline) -->
<div class="form-group"><label class="col-md-4 control-label" for="radios">10b. If yes, Was the skin layer closed?</label>
<div class="col-md-4"><label class="radio-inline" for="radios-0"> <input type="radio" name="radios" id="radios-0" value="1" checked="checked" /> Yes </label> <label class="radio-inline" for="radios-1"> <input type="radio" name="radios" id="radios-1" value="2" /> No </label> <label class="radio-inline" for="radios-2"> <input type="radio" name="radios" id="radios-2" value="3" /> Not reported </label></div>
</div>
<!-- Select Basic -->
<div class="form-group"><label class="col-md-4 control-label" for="selectbasic">10bi. If yes, what suture material was used to close the muscle layer? </label>
<div class="col-md-4"><select id="selectbasic" name="selectbasic" class="form-control">
<option value="1">Resorbable suture</option>
<option value="2">Non-absorbable suture</option>
<option value="3">Tissue glue</option>
<option value="4">Staples</option>
<option value="5">Others</option>
</select><em><span class="help-block"> </span></em></div>
</div>
<!-- Multiple Radios (inline) -->
<div class="form-group"><label class="col-md-4 control-label" for="radios">11. Were the skin sutures removed?</label>
<div class="col-md-4"><label class="radio-inline" for="radios-0"> <input type="radio" name="radios" id="radios-0" value="1" checked="checked" /> Yes </label> <label class="radio-inline" for="radios-1"> <input type="radio" name="radios" id="radios-1" value="2" /> No </label> <label class="radio-inline" for="radios-2"> <input type="radio" name="radios" id="radios-2" value="3" /> Not reported </label></div>
</div>
<!-- Multiple Radios (inline) -->
<div class="form-group"><label class="col-md-4 control-label" for="radios">11a. If yes, Were an anaesthic preformed?</label>
<div class="col-md-4"><label class="radio-inline" for="radios-0"> <input type="radio" name="radios" id="radios-0" value="1" checked="checked" /> Yes </label> <label class="radio-inline" for="radios-1"> <input type="radio" name="radios" id="radios-1" value="2" /> No </label> <label class="radio-inline" for="radios-2"> <input type="radio" name="radios" id="radios-2" value="3" /> Not reported </label></div>
</div>
<!-- Textarea -->
<div class="form-group"><label class="col-md-4 control-label" for="textarea">11b. If yes, On what postoperative day were the sutures removed??</label>
<div class="col-md-4"><textarea class="form-control" id="textarea" name="textarea">in days</textarea> <label class="radio-inline" for="radios-2"> <input type="radio" name="radios" id="radios-2" value="3" /> Not reported </label></div>
</div>
<!-- Textarea -->
<div class="form-group"><label class="col-md-4 control-label" for="textarea">12. What was the operative experience of the surgeon?</label>
<div class="col-md-4"><textarea class="form-control" id="textarea" name="textarea">in months</textarea> <label class="radio-inline" for="radios-2"> <input type="radio" name="radios" id="radios-2" value="3" /> Not reported </label></div>
</div>
Assessment of sex as a biological variable in an individual study
Basic Reporting
<!-- Multiple Radios -->
<div class="form-group">
<label class="col-md-4 control-label" for="radios">1. Does the study report sex of experimental animals in title or abstract?</label>
<div class="col-md-4">
<div class="radio">
<label for="radios-0">
<input type="radio" name="radios" id="radios-0" value="1" checked="checked">
Yes
</label>
</div>
<div class="radio">
<label for="radios-1">
<input type="radio" name="radios" id="radios-1" value="2">
No
</label>
</div>
</div>
</div>
<!-- Multiple Radios -->
<div class="form-group">
<label class="col-md-4 control-label" for="radios">2. Does the study report sex of animals in the main manuscript? </label>
<div class="col-md-4">
<div class="radio">
<label for="radios-0">
<input type="radio" name="radios" id="radios-0" value="1" checked="checked">
Yes
</label>
</div>
<div class="radio">
<label for="radios-1">
<input type="radio" name="radios" id="radios-1" value="2">
No
</label>
</div>
</div>
</div>
<!-- Multiple Radios (inline)-->
<div class="form-group">
<label class="col-md-4 control-label" for="radios">2a. If yes, is it a single-sex study </label>
<div class="col-md-4">
<div class="radio">
<label for="radios-0">
<input type="radio" name="radios" id="radios-0" value="1" checked="checked">
Yes
</label>
</div>
<div class="radio">
<label for="radios-1">
<input type="radio" name="radios" id="radios-1" value="2">
No
</label>
</div>
</div>
</div>
<!-- Multiple Radios (inline)-->
<div class="form-group">
<label class="col-md-4 control-label" for="radios">2a.i.If yes:</label>
<div class="col-md-4">
<div class="radio">
<label for="radios-0">
<input type="radio" name="radios" id="radios-0" value="1" checked="checked">
Male
</label>
</div>
<div class="radio">
<label for="radios-1">
<input type="radio" name="radios" id="radios-1" value="2">
Female
</label>
</div>
</div>
</div>
<!-- Multiple Radios -->
<div class="form-group">
<label class="col-md-4 control-label" for="radios">2a.ii. If yes, Is the reason to include animals from only one sex reported?</label>
<div class="col-md-4">
<div class="radio">
<label for="radios-0">
<input type="radio" name="radios" id="radios-0" value="1" checked="checked">
Yes
</label>
</div>
<div class="radio">
<label for="radios-1">
<input type="radio" name="radios" id="radios-1" value="2">
No
</label>
</div>
</div>
</div>
<!-- Textarea -->
<div class="form-group">
<label class="col-md-4 control-label" for="textarea">2a.ii.1. If yes, please, quote. (Leave blank if not reported)</label>
<div class="col-md-4">
<textarea class="form-control" id="textarea" name="textarea"></textarea>
</div>
</div>
<!-- Multiple Radios -->
<div class="form-group">
<label class="col-md-4 control-label" for="radios">2a.iii. If yes, are limitations in single-sex studies discussed? </label>
<div class="col-md-4">
<div class="radio">
<label for="radios-0">
<input type="radio" name="radios" id="radios-0" value="1" checked="checked">
Yes
</label>
</div>
<div class="radio">
<label for="radios-1">
<input type="radio" name="radios" id="radios-1" value="2">
No
</label>
</div>
</div>
</div>
<!-- Textarea -->
<div class="form-group">
<label class="col-md-4 control-label" for="textarea">2a.iii.a. If yes, please quote. (Leave blank if not reported)</label>
<div class="col-md-4">
<textarea class="form-control" id="textarea" name="textarea"></textarea>
</div>
</div>
Contextualization
<!-- Multiple Radios -->
<div class="form-group">
<label class="col-md-4 control-label" for="radios">3. Does the study cite earlier studies that support the existence (or lack) of significant differences between males and females? </label>
<div class="col-md-4">
<div class="radio">
<label for="radios-0">
<input type="radio" name="radios" id="radios-0" value="1" checked="checked">
Yes
</label>
</div>
<div class="radio">
<label for="radios-1">
<input type="radio" name="radios" id="radios-1" value="2">
No
</label>
</div>
</div>
</div>
<!-- Multiple Radios -->
<div class="form-group">
<label class="col-md-4 control-label" for="radios">4. Does the study consider whether the mechanism under investigation is present in both sexes? </label>
<div class="col-md-4">
<div class="radio">
<label for="radios-0">
<input type="radio" name="radios" id="radios-0" value="1" checked="checked">
Yes
</label>
</div>
<div class="radio">
<label for="radios-1">
<input type="radio" name="radios" id="radios-1" value="2">
No
</label>
</div>
</div>
</div>
<!-- Multiple Radios -->
<div class="form-group">
<label class="col-md-4 control-label" for="radios">5. Does the study reflect on important sex-specific epidemiologic distributions in neuropathic pain prevalence in the human population?</label>
<div class="col-md-4">
<div class="radio">
<label for="radios-0">
<input type="radio" name="radios" id="radios-0" value="1" checked="checked">
Yes
</label>
</div>
<div class="radio">
<label for="radios-1">
<input type="radio" name="radios" id="radios-1" value="2">
No
</label>
</div>
</div>
</div>
<!-- Textarea -->
<div class="form-group">
<label class="col-md-4 control-label" for="textarea">5a. If yes, please, quote.</label>
<div class="col-md-4">
<textarea class="form-control" id="textarea" name="textarea"></textarea>
</div>
</div>
<!-- Multiple Radios -->
<div class="form-group">
<label class="col-md-4 control-label" for="radios">6. Does the study reflect on the potentially sex-biased development of the animal model or pre-existing evidence?</label>
<div class="col-md-4">
<div class="radio">
<label for="radios-0">
<input type="radio" name="radios" id="radios-0" value="1" checked="checked">
Yes
</label>
</div>
<div class="radio">
<label for="radios-1">
<input type="radio" name="radios" id="radios-1" value="2">
No
</label>
</div>
</div>
</div>
<!-- Multiple Radios -->
<div class="form-group">
<label class="col-md-4 control-label" for="radios">7. Did authors conclude that sex-specific research is warranted?</label>
<div class="col-md-4">
<div class="radio">
<label for="radios-0">
<input type="radio" name="radios" id="radios-0" value="1" checked="checked">
Yes
</label>
</div>
<div class="radio">
<label for="radios-1">
<input type="radio" name="radios" id="radios-1" value="2">
No
</label>
</div>
</div>
</div>
<!-- Multiple Checkboxes -->
<div class="form-group">
<label class="col-md-4 control-label" for="checkboxes">8. Did the authors use the term “sex” or “gender”?</label>
<div class="col-md-4">
<div class="checkbox">
<label for="checkboxes-0">
<input type="checkbox" name="checkboxes" id="checkboxes-0" value="1">
used “sex” only
</label>
</div>
<div class="checkbox">
<label for="checkboxes-1">
<input type="checkbox" name="checkboxes" id="checkboxes-1" value="2">
used “gender” only
</label>
</div>
<div class="checkbox">
<label for="checkboxes-2">
<input type="checkbox" name="checkboxes" id="checkboxes-2" value="3">
used both terms
</label>
</div>
<div class="checkbox">
<label for="checkboxes-3">
<input type="checkbox" name="checkboxes" id="checkboxes-3" value="4">
used neither terms
</label>
</div>
</div>
</div>
Housing/Animal model
<!-- Multiple Radios -->
<div class="form-group">
<label class="col-md-4 control-label" for="radios">9. Do the author consider it important to control for the cyclicity of female rodents?</label>
<div class="col-md-4">
<div class="radio">
<label for="radios-0">
<input type="radio" name="radios" id="radios-0" value="1" checked="checked">
Yes
</label>
</div>
<div class="radio">
<label for="radios-1">
<input type="radio" name="radios" id="radios-1" value="2">
No
</label>
</div>
</div>
</div>
<!-- Multiple Checkboxes -->
<div class="form-group">
<label class="col-md-4 control-label" for="checkboxes">9a. If yes, do they consider it important to consider hormonal status in</label>
<div class="col-md-4">
<div class="checkbox">
<label for="checkboxes-0">
<input type="checkbox" name="checkboxes" id="checkboxes-0" value="1">
Female rodents
</label>
</div>
<div class="checkbox">
<label for="checkboxes-1">
<input type="checkbox" name="checkboxes" id="checkboxes-1" value="2">
Male rodents
</label>
</div>
<div class="checkbox">
<label for="checkboxes-2">
<input type="checkbox" name="checkboxes" id="checkboxes-2" value="3">
Both
</label>
</div>
</div>
</div>
<!-- Multiple Radios -->
<div class="form-group">
<label class="col-md-4 control-label" for="radios">10. Is a method for documenting the hormonal status of the experimental animals described?</label>
<div class="col-md-4">
<div class="radio">
<label for="radios-0">
<input type="radio" name="radios" id="radios-0" value="1" checked="checked">
Yes
</label>
</div>
<div class="radio">
<label for="radios-1">
<input type="radio" name="radios" id="radios-1" value="2">
No
</label>
</div>
</div>
</div>
<!-- Multiple Radios -->
<div class="form-group">
<label class="col-md-4 control-label" for="radios">11. Are different housing conditions described for male and female animals? </label>
<div class="col-md-4">
<div class="radio">
<label for="radios-0">
<input type="radio" name="radios" id="radios-0" value="1" checked="checked">
Yes
</label>
</div>
<div class="radio">
<label for="radios-1">
<input type="radio" name="radios" id="radios-1" value="2">
No
</label>
</div>
<div class="radio">
<label for="radios-2">
<input type="radio" name="radios" id="radios-2" value="3">
Not applicable
</label>
</div>
</div>
</div>
Study design/ statistical analysis/ Experimental set-up
<!-- Multiple Radios -->
<div class="form-group">
<label class="col-md-4 control-label" for="radios">12. Did the study have a factorial design with sex as a factor?</label>
<div class="col-md-4">
<div class="radio">
<label for="radios-0">
<input type="radio" name="radios" id="radios-0" value="1" checked="checked">
Yes
</label>
</div>
<div class="radio">
<label for="radios-1">
<input type="radio" name="radios" id="radios-1" value="2">
No
</label>
</div>
<div class="radio">
<label for="radios-2">
<input type="radio" name="radios" id="radios-2" value="3">
Not applicable
</label>
</div>
</div>
</div>
<!-- Textarea -->
<div class="form-group">
<label class="col-md-4 control-label" for="textarea">12a. If yes, state the design (group level x factor level) </label>
<div class="col-md-4">
<textarea class="form-control" id="textarea" name="textarea"></textarea>
</div>
</div>
<!-- Textarea -->
<div class="form-group">
<label class="col-md-4 control-label" for="textarea">12b. If no, describe the design</label>
<div class="col-md-4">
<textarea class="form-control" id="textarea" name="textarea"></textarea>
</div>
</div>
<!-- Multiple Radios -->
<div class="form-group">
<label class="col-md-4 control-label" for="radios">13. Did the authors consider the influence of sex chromosomes? </label>
<div class="col-md-4">
<div class="radio">
<label for="radios-0">
<input type="radio" name="radios" id="radios-0" value="1" checked="checked">
Yes
</label>
</div>
<div class="radio">
<label for="radios-1">
<input type="radio" name="radios" id="radios-1" value="2">
No
</label>
</div>
</div>
</div>
<!-- Multiple Radios -->
<div class="form-group">
<label class="col-md-4 control-label" for="radios">13a. If yes, was the influence of sex chromosomes investigated separatedly from gonadal hormones? </label>
<div class="col-md-4">
<div class="radio">
<label for="radios-0">
<input type="radio" name="radios" id="radios-0" value="1" checked="checked">
Yes
</label>
</div>
<div class="radio">
<label for="radios-1">
<input type="radio" name="radios" id="radios-1" value="2">
No
</label>
</div>
</div>
</div>
<!-- Multiple Radios -->
<div class="form-group">
<label class="col-md-4 control-label" for="radios">14. Did the authors consider the influence of sex hormones? </label>
<div class="col-md-4">
<div class="radio">
<label for="radios-0">
<input type="radio" name="radios" id="radios-0" value="1" checked="checked">
Yes
</label>
</div>
<div class="radio">
<label for="radios-1">
<input type="radio" name="radios" id="radios-1" value="2">
No
</label>
</div>
</div>
</div>
Sample size
<!-- Multiple Radios -->
<div class="form-group">
<label class="col-md-4 control-label" for="radios">15. Was the prior sample size specified for sex? </label>
<div class="col-md-4">
<div class="radio">
<label for="radios-0">
<input type="radio" name="radios" id="radios-0" value="1" checked="checked">
Yes
</label>
</div>
<div class="radio">
<label for="radios-1">
<input type="radio" name="radios" id="radios-1" value="2">
No
</label>
</div>
<div class="radio">
<label for="radios-2">
<input type="radio" name="radios" id="radios-2" value="3">
Not applicable
</label>
</div>
</div>
</div>
<!-- Textarea -->
<div class="form-group">
<label class="col-md-4 control-label" for="textarea">16. Total number of experimental groups: </label>
<div class="col-md-4">
<textarea class="form-control" id="textarea" name="textarea"></textarea>
</div>
</div>
<!-- Textarea -->
<div class="form-group">
<label class="col-md-4 control-label" for="textarea">17. Number of interventional groups: </label>
<div class="col-md-4">
<textarea class="form-control" id="textarea" name="textarea"></textarea>
</div>
</div>
<!-- Textarea -->
<div class="form-group">
<label class="col-md-4 control-label" for="textarea">18. Number of control groups:</label>
<div class="col-md-4">
<textarea class="form-control" id="textarea" name="textarea"></textarea>
</div>
</div>
<!-- Multiple Radios -->
<div class="form-group">
<label class="col-md-4 control-label" for="radios">19. Did the authors consider that their study design might lack power to detect interactions? </label>
<div class="col-md-4">
<div class="radio">
<label for="radios-0">
<input type="radio" name="radios" id="radios-0" value="1" checked="checked">
Yes
</label>
</div>
<div class="radio">
<label for="radios-1">
<input type="radio" name="radios" id="radios-1" value="2">
No
</label>
</div>
<div class="radio">
<label for="radios-2">
<input type="radio" name="radios" id="radios-2" value="3">
Not applicable
</label>
</div>
</div>
</div>
Statistical analysis
<!-- Multiple Radios -->
<div class="form-group">
<label class="col-md-4 control-label" for="radios">20. Did the authors perform a statistical analysis taking into account SABV?</label>
<div class="col-md-4">
<div class="radio">
<label for="radios-0">
<input type="radio" name="radios" id="radios-0" value="1" checked="checked">
Yes
</label>
</div>
<div class="radio">
<label for="radios-1">
<input type="radio" name="radios" id="radios-1" value="2">
No
</label>
</div>
<div class="radio">
<label for="radios-2">
<input type="radio" name="radios" id="radios-2" value="3">
Not applicable
</label>
</div>
</div>
</div>
<!-- Multiple Checkboxes -->
<div class="form-group">
<label class="col-md-4 control-label" for="checkboxes">20a. If yes, did they plan to:</label>
<div class="col-md-4">
<div class="checkbox">
<label for="checkboxes-0">
<input type="checkbox" name="checkboxes" id="checkboxes-0" value="1">
include sex as a covariate/fixed factor
</label>
</div>
<div class="checkbox">
<label for="checkboxes-1">
<input type="checkbox" name="checkboxes" id="checkboxes-1" value="2">
test for interaction
</label>
</div>
<div class="checkbox">
<label for="checkboxes-2">
<input type="checkbox" name="checkboxes" id="checkboxes-2" value="3">
compare sex within treatment/control
</label>
</div>
<div class="checkbox">
<label for="checkboxes-3">
<input type="checkbox" name="checkboxes" id="checkboxes-3" value="4">
compare treatment/control within sex
</label>
</div>
<div class="checkbox">
<label for="checkboxes-4">
<input type="checkbox" name="checkboxes" id="checkboxes-4" value="5">
other
</label>
</div>
</div>
</div>
<!-- Textarea -->
<div class="form-group">
<label class="col-md-4 control-label" for="textarea">20b. If others, please cite:</label>
<div class="col-md-4">
<textarea class="form-control" id="textarea" name="textarea"></textarea>
</div>
</div>
<!-- Multiple Checkboxes -->
<div class="form-group">
<label class="col-md-4 control-label" for="checkboxes">21. Were sexes pooled?</label>
<div class="col-md-4">
<div class="checkbox">
<label for="checkboxes-0">
<input type="checkbox" name="checkboxes" id="checkboxes-0" value="1">
Not applicable
</label>
</div>
<div class="checkbox">
<label for="checkboxes-1">
<input type="checkbox" name="checkboxes" id="checkboxes-1" value="2">
analyzed sex separately throughout
</label>
</div>
<div class="checkbox">
<label for="checkboxes-2">
<input type="checkbox" name="checkboxes" id="checkboxes-2" value="3">
pooled at least for some analysis
</label>
</div>
</div>
</div>
<!-- Multiple Checkboxes -->
<div class="form-group">
<label class="col-md-4 control-label" for="checkboxes">21a. If 'analyzed sex separately throughout' (answer B)</label>
<div class="col-md-4">
<div class="checkbox">
<label for="checkboxes-0">
<input type="checkbox" name="checkboxes" id="checkboxes-0" value="1">
pooled after finding no difference in testing
</label>
</div>
<div class="checkbox">
<label for="checkboxes-1">
<input type="checkbox" name="checkboxes" id="checkboxes-1" value="2">
pooled without testing for difference
</label>
</div>
<div class="checkbox">
<label for="checkboxes-2">
<input type="checkbox" name="checkboxes" id="checkboxes-2" value="3">
pooled after finding significant difference
</label>
</div>
</div>
</div>
<!-- Multiple Checkboxes -->
<div class="form-group">
<label class="col-md-4 control-label" for="checkboxes">22. If a post-hoc test for a treatment effect within a sex was conducted, was it preceded by a test for interaction? </label>
<div class="col-md-4">
<div class="checkbox">
<label for="checkboxes-0">
<input type="checkbox" name="checkboxes" id="checkboxes-0" value="1">
Not applicable
</label>
</div>
<div class="checkbox">
<label for="checkboxes-1">
<input type="checkbox" name="checkboxes" id="checkboxes-1" value="2">
Yes, for all outcomes
</label>
</div>
<div class="checkbox">
<label for="checkboxes-2">
<input type="checkbox" name="checkboxes" id="checkboxes-2" value="3">
Yes, for some outcomes
</label>
</div>
<div class="checkbox">
<label for="checkboxes-3">
<input type="checkbox" name="checkboxes" id="checkboxes-3" value="4">
No
</label>
</div>
</div>
</div>
<!-- Multiple Checkboxes -->
<div class="form-group">
<label class="col-md-4 control-label" for="checkboxes">23. Were p-values or effect sizes reported for interaction?</label>
<div class="col-md-4">
<div class="checkbox">
<label for="checkboxes-0">
<input type="checkbox" name="checkboxes" id="checkboxes-0" value="1">
Yes
</label>
</div>
<div class="checkbox">
<label for="checkboxes-1">
<input type="checkbox" name="checkboxes" id="checkboxes-1" value="2">
No
</label>
</div>
<div class="checkbox">
<label for="checkboxes-2">
<input type="checkbox" name="checkboxes" id="checkboxes-2" value="3">
Not applicable
</label>
</div>
</div>
</div>
Reporting of results
<!-- Multiple Radios -->
<div class="form-group">
<label class="col-md-4 control-label" for="radios">24. Does the study report sex-disaggregated data in graphs, tables, or raw data (including in supplement) for pain-associated behavioural test?</label>
<div class="col-md-4">
<div class="radio">
<label for="radios-0">
<input type="radio" name="radios" id="radios-0" value="1" checked="checked">
Yes
</label>
</div>
<div class="radio">
<label for="radios-1">
<input type="radio" name="radios" id="radios-1" value="2">
No
</label>
</div>
<div class="radio">
<label for="radios-2">
<input type="radio" name="radios" id="radios-2" value="3">
Not applicable
</label>
</div>
</div>
</div>
<!-- Multiple Radios -->
<div class="form-group">
<label class="col-md-4 control-label" for="radios">25. How are the results from sex-specific analysis labelled? </label>
<div class="col-md-4">
<div class="radio">
<label for="radios-0">
<input type="radio" name="radios" id="radios-0" value="1" checked="checked">
Applicable
</label>
</div>
<div class="radio">
<label for="radios-1">
<input type="radio" name="radios" id="radios-1" value="2">
Not applicable
</label>
</div>
</div>
</div>
<!-- Textarea -->
<div class="form-group">
<label class="col-md-4 control-label" for="textarea">25a. If applicable, please, quote: (Leave blank if not reported)</label>
<div class="col-md-4">
<textarea class="form-control" id="textarea" name="textarea"></textarea>
</div>
</div>
<!-- Multiple Radios -->
<div class="form-group">
<label class="col-md-4 control-label" for="radios">26. Does the study report an effect of the intervention in one or both sex(es)?</label>
<div class="col-md-4">
<div class="radio">
<label for="radios-0">
<input type="radio" name="radios" id="radios-0" value="1" checked="checked">
only in male
</label>
</div>
<div class="radio">
<label for="radios-1">
<input type="radio" name="radios" id="radios-1" value="2">
only in female
</label>
</div>
<div class="radio">
<label for="radios-2">
<input type="radio" name="radios" id="radios-2" value="3">
in both
</label>
</div>
<div class="radio">
<label for="radios-3">
<input type="radio" name="radios" id="radios-3" value="4">
only one sex studied
</label>
</div>
</div>
</div>
<!-- Multiple Radios -->
<div class="form-group">
<label class="col-md-4 control-label" for="radios">27. From which evidence do authors conclude that a difference exists? </label>
<div class="col-md-4">
<div class="radio">
<label for="radios-0">
<input type="radio" name="radios" id="radios-0" value="1" checked="checked">
significant interaction term
</label>
</div>
<div class="radio">
<label for="radios-1">
<input type="radio" name="radios" id="radios-1" value="2">
within each sex, for one sex p a significant effect of treatment was found while this wasn’t the case for the other sex
</label>
</div>
<div class="radio">
<label for="radios-2">
<input type="radio" name="radios" id="radios-2" value="3">
testing sex only within treatment
</label>
</div>
<div class="radio">
<label for="radios-3">
<input type="radio" name="radios" id="radios-3" value="4">
claiming effect without any reporting of statistical analysis
</label>
</div>
</div>
</div>
<!-- Multiple Radios -->
<div class="form-group">
<label class="col-md-4 control-label" for="radios">28. Are the measures to assess the difference provided to the reader? </label>
<div class="col-md-4">
<div class="radio">
<label for="radios-0">
<input type="radio" name="radios" id="radios-0" value="1" checked="checked">
Yes
</label>
</div>
<div class="radio">
<label for="radios-1">
<input type="radio" name="radios" id="radios-1" value="2">
No
</label>
</div>
<div class="radio">
<label for="radios-2">
<input type="radio" name="radios" id="radios-2" value="3">
Not applicable
</label>
</div>
</div>
</div>
<!-- Textarea -->
<div class="form-group">
<label class="col-md-4 control-label" for="textarea">28a. If yes, please extract the respective measure and extract for how many outcomes, if possible. (Leave blank if not reported)</label>
<div class="col-md-4">
<textarea class="form-control" id="textarea" name="textarea">- P-value:
- Effect measure (Cohen’s d, Hedges g, mean difference):
- Effect size:
- Lower 95% confidence bound:
- Upper 95% confidence bound:
</textarea>
</div>
</div>
<!-- Multiple Radios -->
<div class="form-group">
<label class="col-md-4 control-label" for="radios">29. Does the study power for an interaction analysis?</label>
<div class="col-md-4">
<div class="radio">
<label for="radios-0">
<input type="radio" name="radios" id="radios-0" value="1" checked="checked">
Yes
</label>
</div>
<div class="radio">
<label for="radios-1">
<input type="radio" name="radios" id="radios-1" value="2">
No
</label>
</div>
<div class="radio">
<label for="radios-2">
<input type="radio" name="radios" id="radios-2" value="3">
Not applicable
</label>
</div>
</div>
</div>
<!-- Textarea -->
<div class="form-group">
<label class="col-md-4 control-label" for="textarea">29a. If yes, at which power level? </label>
<div class="col-md-4">
<textarea class="form-control" id="textarea" name="textarea"></textarea>
</div>
</div>
<!-- Multiple Radios -->
<div class="form-group">
<label class="col-md-4 control-label" for="radios">30. Does the study discuss the sex-specific results? </label>
<div class="col-md-4">
<div class="radio">
<label for="radios-0">
<input type="radio" name="radios" id="radios-0" value="1" checked="checked">
Yes
</label>
</div>
<div class="radio">
<label for="radios-1">
<input type="radio" name="radios" id="radios-1" value="2">
No
</label>
</div>
<div class="radio">
<label for="radios-2">
<input type="radio" name="radios" id="radios-2" value="3">
Not applicable
</label>
</div>
</div>
</div>
<!-- Textarea -->
<div class="form-group">
<label class="col-md-4 control-label" for="textarea">30a. If yes, please quote:</label>
<div class="col-md-4">
<textarea class="form-control" id="textarea" name="textarea"></textarea>
</div>
</div>
<!-- Multiple Radios -->
<div class="form-group">
<label class="col-md-4 control-label" for="radios">31. Does the study highlight sex difference or the absence of such in the title or abstract?</label>
<div class="col-md-4">
<div class="radio">
<label for="radios-0">
<input type="radio" name="radios" id="radios-0" value="1" checked="checked">
Yes
</label>
</div>
<div class="radio">
<label for="radios-1">
<input type="radio" name="radios" id="radios-1" value="2">
No
</label>
</div>
<div class="radio">
<label for="radios-2">
<input type="radio" name="radios" id="radios-2" value="3">
Not applicable
</label>
</div>
</div>
</div>
Meta-Daten
<!-- Multiple Radios -->
<div class="form-group">
<label class="col-md-4 control-label" for="radios">32. Is the country of the first author's university affiliation given?</label>
<div class="col-md-4">
<div class="radio">
<label for="radios-0">
<input type="radio" name="radios" id="radios-0" value="1" checked="checked">
Yes
</label>
</div>
<div class="radio">
<label for="radios-1">
<input type="radio" name="radios" id="radios-1" value="2">
No
</label>
</div>
</div>
</div>
<!-- Textarea -->
<div class="form-group">
<label class="col-md-4 control-label" for="textarea">32a. If yes, please, quote:</label>
<div class="col-md-4">
<textarea class="form-control" id="textarea" name="textarea"></textarea>
</div>
</div>
<!-- Multiple Radios -->
<div class="form-group">
<label class="col-md-4 control-label" for="radios">33. Are there female author(s) in this study?</label>
<div class="col-md-4">
<div class="radio">
<label for="radios-0">
<input type="radio" name="radios" id="radios-0" value="1" checked="checked">
Yes
</label>
</div>
<div class="radio">
<label for="radios-1">
<input type="radio" name="radios" id="radios-1" value="2">
No
</label>
</div>
</div>
</div>
<!-- Multiple Checkboxes -->
<div class="form-group">
<label class="col-md-4 control-label" for="checkboxes">33a. If yes, please extract the type of authorship. (If there are female co-authors, please extract the number of co-authors)</label>
<div class="col-md-4">
<div class="checkbox">
<label for="checkboxes-0">
<input type="checkbox" name="checkboxes" id="checkboxes-0" value="1">
female first author
</label>
</div>
<div class="checkbox">
<label for="checkboxes-1">
<input type="checkbox" name="checkboxes" id="checkboxes-1" value="2">
female last author
</label>
</div>
<div class="checkbox">
<label for="checkboxes-2">
<input type="checkbox" name="checkboxes" id="checkboxes-2" value="3">
female co-author
</label>
</div>
</div>
</div>
<!-- Textarea -->
<div class="form-group">
<label class="col-md-4 control-label" for="textarea">33a.i. If female co-author, please extract the number of the female co-author(s)</label>
<div class="col-md-4">
<textarea class="form-control" id="textarea" name="textarea"></textarea>
</div>
</div>
Risk of bias assessment
<!-- Multiple Radios -->
<div class="form-group">
<label class="col-md-4 control-label" for="radios">1. Were the ARRIVE guidelines followed?</label>
<div class="col-md-4">
<div class="radio">
<label for="radios-0">
<input type="radio" name="radios" id="radios-0" value="1" checked="checked">
Yes
</label>
</div>
<div class="radio">
<label for="radios-1">
<input type="radio" name="radios" id="radios-1" value="2">
No
</label>
</div>
<div class="radio">
<label for="radios-2">
<input type="radio" name="radios" id="radios-2" value="3">
Not reported
</label>
</div>
</div>
</div>
<!-- Multiple Radios -->
<div class="form-group">
<label class="col-md-4 control-label" for="radios">2. Were the animals randomly assigned to the experimental group?</label>
<div class="col-md-4">
<div class="radio">
<label for="radios-0">
<input type="radio" name="radios" id="radios-0" value="1" checked="checked">
Yes
</label>
</div>
<div class="radio">
<label for="radios-1">
<input type="radio" name="radios" id="radios-1" value="2">
No
</label>
</div>
<div class="radio">
<label for="radios-2">
<input type="radio" name="radios" id="radios-2" value="3">
Not reported
</label>
</div>
</div>
</div>
<!-- Multiple Radios -->
<div class="form-group">
<label class="col-md-4 control-label" for="radios">2a. If yes, has the method of randomization been reported?</label>
<div class="col-md-4">
<div class="radio">
<label for="radios-0">
<input type="radio" name="radios" id="radios-0" value="1" checked="checked">
Yes
</label>
</div>
<div class="radio">
<label for="radios-1">
<input type="radio" name="radios" id="radios-1" value="2">
No
</label>
</div>
</div>
</div>
<!-- Multiple Radios -->
<div class="form-group">
<label class="col-md-4 control-label" for="radios">3. Was the group assignment for the investigator concealed?</label>
<div class="col-md-4">
<div class="radio">
<label for="radios-0">
<input type="radio" name="radios" id="radios-0" value="1" checked="checked">
Yes
</label>
</div>
<div class="radio">
<label for="radios-1">
<input type="radio" name="radios" id="radios-1" value="2">
No
</label>
</div>
<div class="radio">
<label for="radios-2">
<input type="radio" name="radios" id="radios-2" value="3">
Not reported
</label>
</div>
</div>
</div>
<!-- Textarea -->
<div class="form-group">
<label class="col-md-4 control-label" for="textarea">3a. If yes, please quote. (Leave blank if not reported)</label>
<div class="col-md-4">
<textarea class="form-control" id="textarea" name="textarea"></textarea>
</div>
</div>
<!-- Multiple Radios -->
<div class="form-group">
<label class="col-md-4 control-label" for="radios">4. Were the animal caretakers and investigators conducting the experiments be blinded to the allocation sequence?</label>
<div class="col-md-4">
<div class="radio">
<label for="radios-0">
<input type="radio" name="radios" id="radios-0" value="1" checked="checked">
Yes
</label>
</div>
<div class="radio">
<label for="radios-1">
<input type="radio" name="radios" id="radios-1" value="2">
No
</label>
</div>
<div class="radio">
<label for="radios-2">
<input type="radio" name="radios" id="radios-2" value="3">
Not reported
</label>
</div>
</div>
</div>
<!-- Multiple Radios -->
<div class="form-group">
<label class="col-md-4 control-label" for="radios">5. Were the investigators blinded to the assessment, measurement or quantifying the experimental outcome?</label>
<div class="col-md-4">
<div class="radio">
<label for="radios-0">
<input type="radio" name="radios" id="radios-0" value="1" checked="checked">
Yes
</label>
</div>
<div class="radio">
<label for="radios-1">
<input type="radio" name="radios" id="radios-1" value="2">
No
</label>
</div>
<div class="radio">
<label for="radios-2">
<input type="radio" name="radios" id="radios-2" value="3">
Not reported
</label>
</div>
</div>
</div>
<!-- Multiple Radios -->
<div class="form-group">
<label class="col-md-4 control-label" for="radios">6. Has there been a sample size calculation when the study is being designed?</label>
<div class="col-md-4">
<div class="radio">
<label for="radios-0">
<input type="radio" name="radios" id="radios-0" value="1" checked="checked">
Yes
</label>
</div>
<div class="radio">
<label for="radios-1">
<input type="radio" name="radios" id="radios-1" value="2">
No
</label>
</div>
<div class="radio">
<label for="radios-2">
<input type="radio" name="radios" id="radios-2" value="3">
Not reported
</label>
</div>
</div>
</div>
<!-- Textarea -->
<div class="form-group">
<label class="col-md-4 control-label" for="textarea">6a. If yes, please quote (incl. the method)</label>
<div class="col-md-4">
<textarea class="form-control" id="textarea" name="textarea"></textarea>
</div>
</div>
<!-- Multiple Radios -->
<div class="form-group">
<label class="col-md-4 control-label" for="radios">7. Were rules for stopping data collection defined in advance?</label>
<div class="col-md-4">
<div class="radio">
<label for="radios-0">
<input type="radio" name="radios" id="radios-0" value="1" checked="checked">
Yes
</label>
</div>
<div class="radio">
<label for="radios-1">
<input type="radio" name="radios" id="radios-1" value="2">
No
</label>
</div>
<div class="radio">
<label for="radios-2">
<input type="radio" name="radios" id="radios-2" value="3">
Not reported
</label>
</div>
</div>
</div>
<!-- Multiple Radios -->
<div class="form-group">
<label class="col-md-4 control-label" for="radios">8. Have any excluded animals been reported?</label>
<div class="col-md-4">
<div class="radio">
<label for="radios-0">
<input type="radio" name="radios" id="radios-0" value="1" checked="checked">
Yes
</label>
</div>
<div class="radio">
<label for="radios-1">
<input type="radio" name="radios" id="radios-1" value="2">
No
</label>
</div>
<div class="radio">
<label for="radios-2">
<input type="radio" name="radios" id="radios-2" value="3">
Not reported
</label>
</div>
</div>
</div>
<!-- Textarea -->
<div class="form-group">
<label class="col-md-4 control-label" for="textarea">8a. If yes, please quote (incl. attrition or exclusion) (Leave blank if not reported)</label>
<div class="col-md-4">
<textarea class="form-control" id="textarea" name="textarea"></textarea>
</div>
</div>
<!-- Multiple Radios -->
<div class="form-group">
<label class="col-md-4 control-label" for="radios">9. Were definition and handling of outliers defined when the study is being designed?</label>
<div class="col-md-4">
<div class="radio">
<label for="radios-0">
<input type="radio" name="radios" id="radios-0" value="1" checked="checked">
Yes
</label>
</div>
<div class="radio">
<label for="radios-1">
<input type="radio" name="radios" id="radios-1" value="2">
No
</label>
</div>
<div class="radio">
<label for="radios-2">
<input type="radio" name="radios" id="radios-2" value="3">
Not reported
</label>
</div>
</div>
</div>
<!-- Multiple Radios -->
<div class="form-group">
<label class="col-md-4 control-label" for="radios">10. Was the number of performed stimuli reported?</label>
<div class="col-md-4">
<div class="radio">
<label for="radios-0">
<input type="radio" name="radios" id="radios-0" value="1" checked="checked">
Yes
</label>
</div>
<div class="radio">
<label for="radios-1">
<input type="radio" name="radios" id="radios-1" value="2">
No
</label>
</div>
<div class="radio">
<label for="radios-2">
<input type="radio" name="radios" id="radios-2" value="3">
Not reported
</label>
</div>
</div>
</div>
<!-- Textarea -->
<div class="form-group">
<label class="col-md-4 control-label" for="textarea">10a. If yes, please extract the number of stimuli</label>
<div class="col-md-4">
<textarea class="form-control" id="textarea" name="textarea"></textarea>
</div>
</div>
<!-- Multiple Radios -->
<div class="form-group">
<label class="col-md-4 control-label" for="radios">11. Are funding sources reported? </label>
<div class="col-md-4">
<div class="radio">
<label for="radios-0">
<input type="radio" name="radios" id="radios-0" value="1" checked="checked">
Yes
</label>
</div>
<div class="radio">
<label for="radios-1">
<input type="radio" name="radios" id="radios-1" value="2">
No
</label>
</div>
</div>
</div>
<!-- Multiple Radios -->
<div class="form-group">
<label class="col-md-4 control-label" for="radios">11a. If yes, please extract the type of funding</label>
<div class="col-md-4">
<div class="radio">
<label for="radios-0">
<input type="radio" name="radios" id="radios-0" value="1" checked="checked">
public
</label>
</div>
<div class="radio">
<label for="radios-1">
<input type="radio" name="radios" id="radios-1" value="2">
corporate
</label>
</div>
<div class="radio">
<label for="radios-2">
<input type="radio" name="radios" id="radios-2" value="3">
other
</label>
</div>
</div>
</div>
<!-- Textarea -->
<div class="form-group">
<label class="col-md-4 control-label" for="textarea">11b. If yes, please extract the name of the funder(s).</label>
<div class="col-md-4">
<textarea class="form-control" id="textarea" name="textarea"></textarea>
</div>
</div>
